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All authors have given final approval of the version to be published. Product information Technical Details. For an individual heavy consumer of either heroin or alcohol, the risk of dying from a heroin overdose or from alcoholic cirrhosis increased considerably in each case. Prevalence data was available for all drugs except methadone; and amphetamine and methamphetamine were grouped together. The sensitivity analysis data for tolerant users are additionally shown in Figure 1 — 3 based on the ratio between no-tolerance and high tolerance dosage as shown in Table 2 27 , 37 , 42 , 43 , 44 , 45 , 46 , 47 , 48 , 49 , 50 , 51 , 52 , 53 ,
Table 2 Exposure data selected for calculating the margin of exposure see Supplementary Table S1 online for distribution functions used for calculation. Savage Love Aug 10, The sensitivity analysis based on human data for ethanol shows that the average MOE result is similar to the result based on animal LD Drug Policy 22 , — Shopbop Designer Fashion Brands. Patterned, semi-opaque tights with a matte finish, with an extra reinforced panty portion. Addiction Treatment Forum 12 , 1—8